In this issue, Ishikawa and colleagues provide direct evidence to support the 'winch' hypothesis for the dynein motor mechanism, in which the AAA domain motor unit is displaced parallel to the ...

Cytoplasmic dynein is a vital microtubule-based motor protein that drives retrograde intracellular transport, supporting essential cellular functions ranging from organelle positioning to cell ...

At the HOT ROD How-To section, you’ll learn how to make improvements to your own special hot rod, drawing from the DIY knowledge of the HOT ROD team to learn more about how-to make more power ...