Chromatin immunoprecipitation (ChIP) is a technique for identifying and characterizing elements in protein-DNA interactions involved in gene regulation or chromatin organization. Microarray ...

In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...

Rheumatoid arthritis (RA) is an inflammatory arthritis characterized by chronic joint inflammation, cartilage degradation, and bone erosion.

Rheumatoid arthritis (RA) is an inflammatory arthritis characterized by chronic joint inflammation, cartilage degradation, and bone erosion. ELK3 is a ...

Results prove that inversions can be generated in plants without causing further unwanted changes in the expression of genetic information.

The discovery of a family with sequence similarity 102 member A (Fam102a) protein as a novel bone remodeling factor that regulates both osteoclast and osteoblast differentiation can aid the ...

Patience does pay off, as Robert Kingston and his postdoctoral fellow Jérôme Déjardin from Harvard Medical School can attest. Kingston has a longstanding interest in protein-mediated chromatin ...

In subsequent experiments, the scientists employed co-immunoprecipitation assay, a biochemistry-based method to identify protein-protein interactions. The analysis revealed significant binding ...

Dual luciferase reporter assays and chromatin immunoprecipitation were performed to identify whether SMAD4 functioned as a transcription factor for phosphoglycerate kinase 1 (PGK1) in PDAC cells.

It was also validated in vivo and in vitro by co-immunoprecipitation (Co-IP), immunohistochemistry, and Western blotting. Results CA significantly alleviated clinical activity and histological changes ...

Despite the established links between inflammation and cancer development, the effects of inflammatory signaling on cancer ...

This manuscript describes an important finding of the transcriptional control of a chimeric gene transfer agents (GTA) cluster in Bartonella by a processive anti-termination factor (BrrG). The ...