Frontiers12d
PRDM1 Drives Human Primary T Cell Hyporesponsiveness by Altering the T Cell Transcriptome and Epigenome
Several T cell inhibitory signals have been demonstrated to play a role in GVHD mouse models, such as PRDM1, and a lack of Prdm1 was found to shorten the life span of GVHD mice (1). However, the role ...
eLife10d
GATA6 regulates WNT and BMP programs to pattern precardiac mesoderm during the earliest stages of human cardiogenesis
This important study investigates the function of a critical regulator of human early cardiac development. The convincing examination of GATA6 function is thorough and well-executed. The study will be ...
Frontiers12d
Single-Cell RNA Sequencing Identifies New Inflammation-Promoting Cell Subsets in Asian Patients With Chronic Periodontitis
Cells were then stained with NLRP3 (1:100, IC7578S-100UG, Novus, St. Louis, MO, USA), C1QA (1:100, NB100-64597, Novus), and PRDM1 (1:100, 565276, BD Bioscience) antibodies. Data were acquired within 2 ...