Most people take batteries for granted without ever thinking about the significance of the positive and negative terminals or if they're even needed.

In this study we have investigated the terminal B-cell differentiation phenotype in 60 mantle cell lymphomas, 41 SOX11-positive and 19 SOX11-negative.

Using two unipolar dc supplies in an anti-series configuration is another approach for generating positive and negative voltage—and one that doesn't suffer from power interruption.

The positive and negative terminals are foundational to how a battery works, but the terminals don't necessarily need to be opposite of each other.