Despite challenges in studying allergen-specific CD4+ T cells in food allergy, targeted approaches signal progress while ...

Felix Bayerl is a post-doctoral fellow in Professor Mikaël Pittet's laboratory in the Department of Pathology and Immunology ...

If it has seemed like more people you know are developing diabetes, you are right. The diabetes epidemic is not called that ...

Gut support cells communicate with surprising precision – like brain neurons – using tiny extensions to send instructions to ...

Researchers discovered that people carrying the APOE ε4 gene variant share a unique immune-related protein signature across ...

Arcellx, Inc. advances anito-cel CAR-T therapy for relapsed/refractory multiple myeloma. Click for ACLX pivotal trials, FDA progress, and launch potential by 2026.

CD8⁺ T cells are the immune system's frontline warriors, charged with detecting and eliminating cancer cells. But in the hostile and chronic environment of tumors, these cells often falter.

Parallel proteomics and transcriptomics data reveal that PIM kinases have a context-dependent role in promoting mouse CD8 T cell protein translation, effector function, and cell homing.

Here, Freeman discusses how anito-cel differs from existing CAR T-cell therapies for the treatment of myeloma. Anito-cel utilizes a novel and compact D-Domain binder for targeting BCMA, instead of the ...

Analysis of the survival, proliferation, proteome, and transcriptome of Pim dKO CD8 T cells kept for 6 days in IL-15 showed that PIM1 and PIM2 are dispensable to drive the IL-15-mediated metabolic or ...