Investigating chromatin's 3D architecture reveals its influence on gene regulation, shedding light on mechanisms underlying ...

Each cell in our bodies carries about two meters of DNA in its nucleus, packed into a tiny volume of just a few hundred cubic ...

A cell's nucleus has to hold the entire genome. To do that, the DNA must be carefully arranged and compacted by proteins called histones into a complex known as chromatin. Now scientists have ...

The researchers found chromatin is folded into a variety of tree-like domains spaced along a chromatin backbone. These small and large areas are like a mixed forest of trees growing from the forest ...

Every cancer starts with a single cell, and Jackson Laboratory (JAX) researchers have found a precise and reliable way—whole-genome profiling of open chromatin—to identify the kind of cell ...

During embryonic development and adult life, the plasticity and reversibility of modifications that affect the chromatin structure is important in the expression of genes involved in cell fate ...

“A single-cell atlas of in vivo mammalian chromatin accessibility external link, opens in a new tab.” Cell. Published online August 2, 2018. doi: 10.1016/j.cell.2018.06.052. Hannah A. Pliner et al., ...

Chromatin is the tightly-coiled structure of DNA and proteins which is used to store the genetic information inside the nucleus of a cell. The chromatin in a human cell contains around two metres ...

Researchers at University of California San Diego have produced a single-cell chromatin atlas for the human genome. Chromatin is a complex of DNA and protein found in eukaryotic cells; regions of ...

The instructions to make a cell are encoded in DNA strands that are wrapped in proteins and RNA, and wound together into a 3D structure called chromatin.

Every type of cell has a characteristic chromatin structure that includes closed chromatin, which is tightly wound around nucleosomes and is relatively inactive, and open chromatin, ...