Published (DOI: 10.1038/s41413-025-00418-z) on March 26, 2025, in Bone Research, a groundbreaking study led by KU Leuven in collaboration with international researchers examined bone-forming ...

A fluorescent dye could help scientists listen in on biochemical conversations between cartilage and bone during the earliest stages of osteoarthritis (OA)—even before the disease causes pain.

image: RIP3 plays a pivotal role in the pathogenesis of OA by disrupting cartilage extracellular matrix (ECM) metabolism homeostasis, inhibiting bone formation, and enhancing bone resorption ...