Vacuoles and lysosome-related organelles (LROs) are essential compartments in eukaryotic cells playing crucial roles in storage, degradation, signaling, and homeostasis. Despite their functional ...

Cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) have revolutionized structural biology by enabling high-resolution imaging of biomolecules and cellular structures. However, ...

The study reports the first high-resolution cryo-electron microscopy (cryo-EM) structure of the human MON1A-CCZ1 (HsMC1) complex bound to nucleotide-free RAB7A at a resolution of 2.85 &Aring ...

Harvey Weinstein’s Life Behind Bars: “He’s Still Running Sh**” (Exclusive) On the eve of his New York retrial, the fallen mogul spends 23 hours a day alone in his cell, reading biographies ...

Kyoto, Japan -- There's a sensation that you experience -- near a plane taking off or a speaker bank at a concert -- from a sound so total that you feel it in your very being. When this ...

It begins with observing onion cells, highlighting their components such as the cell wall, nucleus, and vacuoles. Staining techniques reveal the protoplasm, which is essential for life.

While the mechanisms that ensure quick repair of the cell wall are well studied, we as yet understand little about how the vacuole is protected from rupturing upon the sudden change in pressure.

This was done by exposing them to a solution called trypsin-EDTA, which detaches cells from their surface. They found that treating these cells with the toxin latrunculin B, which inhibits the ...

Researchers discovered that SARS-CoV-2-specific T and B cells in long COVID patients are maintained for two years, similar to fully recovered individuals, offering insights into long-term immunity.

Whether activated Potentially Membrane Localized NLRs (PMLs) mediate cell death and calcium influx in a similar way is unknown. We uncovered the cell-death function at the vacuole of an atypical but ...