Add the LAMA inhaler tiotropium and measure FEV 1 in a scheduled follow-up visit 2 weeks later. Tiotropium and a LABA have an additive effect on airway bronchodilatation.

Cardiovascular events in patients with COPD are more likely in those using triple therapy vs ICS/LABA therapy.

No increased risk was observed for ICS monotherapy, and the overall link appeared greater when ICS was used in combinations, such as with a long-acting beta-agonist (LABA) or as triple therapy ...

Citing data published in 2020 and 2021, the sales aid claimed a “49% Observed relative difference with BREZTRI vs LAMA/LABA.” The FDA took a dim view of the suggestion that Breztri had a ...

LAMA-LABA inhaler combinations used by patients in this study included aclidinium-formoterol (Duaklir Pressair, Covis), glycopyrronium-formoterol (Bevespi Aerosphere, AstraZeneca), glycopyrronium ...

These changes highlight the benefit of LABA+LAMA combination therapy and instruct clinicians to immediately escalate to a LABA+LAMA combination once patients no longer meet the criteria for the ...

LAMA/LABA combination therapy for COPD had significantly better outcomes than monotherapy for the 6-minute walking test and number of steps per day.

Data comparing the incidence of severe adverse events among different LAMA/LABA combinations are lacking, they said. In a study published in the journal Chest, the researchers reviewed claims data ...

Inhaled corticosteroids in combination with a LABA definitely have an impact on improving lung function and decreasing the risk of exacerbations, but that has to be weighed against the potential risk.

"The new 2023 GOLD recommendations represent a meaningful change for the treatment of COPD by prioritizing the utilization of a fixed LAMA/LABA combination." ...