Look, I get it. You’ve probably tried a dozen meal plans already and you’re tired of feeling like you’re failing […] The post ...

CRISPR construct to genetically ablate the GABA transporter GAT3 in the mouse visual cortex, with effects on population-level neuronal activity. This work is important, as it sheds light on how GAT3 ...

Inside each cell of the human body are proteins that control which genes are expressed at the right place and time. However, ...

Proteins are life's molecular workhorses, doing everything from turning sunlight into food to fighting viruses. They are ...

A predictive biophysical model that integrates protein-DNA structures and sequences to accurately determine genomic binding sites and affinities of DNA-binding proteins.

Large-scale redesigns, including changes to core domains, may retain stability—challenging assumptions that such regions are off-limits.

Unlike structure-based models, which are limited to a small set of resolved protein-ligand complexes, ProtoBind-Diff leverages a larger pool of chemical and biological data, which helps the model ...

Scientists have discovered a new way to advance drug discovery and diagnostics by targeting a part of the proteome (the ...

Given the amino-acid sequence or 3D structure of a protein, how much can we predict about its function using just a desktop computer? The recent explosive growth in the volume of sequence data and ...

Table of Contents Why Your Body Clock Controls Everything About Performance The Hidden Hormonal Dance That Makes or Breaks ...

In many cases, motor proteins transport cargo in a particular direction along the filament, and this directionality is associated with both protein and filament structure.