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Surprise finding sheds light on what causes Huntington’s disease, a devastating fatal brain disorder
New research shows that the mutation is, surprisingly, harmless for decades. But it quietly grows into a larger mutation — until it eventually crosses a threshold, generates toxic proteins, and
Study finds surprising way that genetic mutation causes Huntington's disease, transforming understanding of the disorder
Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the understanding of the fatal neurodegenerative disorder and suggest potential ways to delay or even prevent it.
New findings shed light on cause of Huntington's disease progression
A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over time, but doesn't start causing harm until it hits a toxic threshold that rapidly leads to the nerve cell’s death.
New Understanding of How Genetic Mutation Causes Huntington’s Disease
Study explains long-standing question of why Huntington’s disease symptoms typically do not appear until midlife even though patients are born with the mutation. Analyses reveal that the repeated DNA sequence driving the disease expands slowly over decades in certain brain cells and then rapidly lengthens and kills the cell.
New Research Sheds Light on the Causes of Huntington’s Disease
If you’ve ever heard of Huntington’s disease, you know how devastating it can be. This hereditary brain disorder slowly robs people of their ability to think, move, and even communicate. The disease’s progression is relentless,
2h
Man gets 19 years in prison for beating girlfriend in Huntington Beach
Conor Bryan Verdun pleaded guilty in October to attempted murder, assault with a deadly weapon and additional felony charges ...
11h
on MSN
Medical mystery solved: Why do some people develop Huntington's earlier than others?
New genetic research shows why some people develop deadly Huntington's disease earlier than others. The findings could lead ...
MedPage Today
2h
Brain Changes Emerge Decades Before Huntington's Diagnosis
Approximately 23 years before a clinical diagnosis, CSF analysis showed very early signs of neurodegeneration with elevated ...
11h
Huntington Bancshares' Profit Surges on Strong Capital Markets, Interest Income Growth
(Reuters) - Huntington Bancshares on Friday reported a more than two-fold rise in its fourth-quarter profit, helped by robust ...
3h
on MSN
Huntington Beach, California Seeks Exemption From Sanctuary City Status
The coastal city's mayor wants to declare it a "non-sanctuary city" the day after President-elect Donald Trump takes office.
Nature
1d
Revealed: Why the fatal Huntington’s gene takes so long to cause harm
Huntington’s is an incurable and fatal genetic condition that progressively affects movement, balance and cognition. It is ...
American Banker
2h
Huntington turns to organic growth as expansion effort clicks
The Columbus, Ohio-based bank's profit more than doubled in the fourth quarter from a year ago, with solid growth in loans and deposits.
C&EN
4h
DNA repeat expansion drives Huntington’s development
Studies of living participants and postmortem brains confirm that gene expansion is a promising target for HD prevention ...
7h
Huntington 'not motivated by price' in sale of historic downtown Columbus buildings
Huntington National Bank could have sold three downtown Columbus buildings for more money, CEO Steve Steinour said, but that was never the point.
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